Download 99mTc-Sestamibi: Clinical Applications by Stefan Guhlke (auth.), Jan Bucerius, Hojjat Ahmadzadehfar, PDF

By Stefan Guhlke (auth.), Jan Bucerius, Hojjat Ahmadzadehfar, Hans-Jürgen Biersack (eds.)

99mTc-sestamibi is a single-photon emission computed tomography (SPECT) radiotracer that's generic for the imaging of myocardial perfusion, in addition to a number of malignant and benign illnesses. 99mTc-Sestamibi – scientific functions offers an in depth and informative evaluate of just about all of the oncologic and non-oncologic functions of 99mTc-sestamibi SPECT, together with a number of rather infrequent symptoms. assorted disease-related protocols for 99mTc-sestamibi SPECT are awarded, and for every sickness a accomplished precis of the correct pathology and epidemiology is equipped. all through, there's a powerful emphasis at the useful points of use of this well known tracer, together with directions for the instruction of numerous commercially on hand tracer kits. scientific practitioners will locate this e-book to be a useful advisor to the appliance and merits of 99mTc-sestamibi SPECT in either the inpatient and the outpatient setting.

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The exposure rates from patients have been worked out by several authors [26, 27]. 0 PSv was measured. 2 PSv. In a PET center handling 18F FDG, 13N Ammonia, and 11C labeled compounds, the average dose to a technologist, handling 831 MBq activity per day, was measured to be 14 PSv. Reference 1. Preuss R, Weise R, Lindner O, Fricke E, Fricke H, Burchert W (2008) Optimisation of protocol for low dose CT-derived attenuation correction in myocardial perfusion SPECT imaging. Eur J Nucl Med Mol Imaging 35:1133–1141.

A 95–97% rate of success was reported with this approach, but the operating time was excessive and the hypocalcemia rates remained near 15%. In recent years, the trend toward less invasive surgery in the management of HPT has become popular among physicians. In 2001, Giordano et al. published a survey on new trends in parathyroid scintigraphy [8]: the authors concluded that parathyroid scintigraphy can be recommended not only in persistent or recurrent hyperparathyroidism, but also in hyperparathyroid patients prior to first surgery.

B, c) Ultrasound with lesion below the right lower pole. (d) Delayed MIBI scan with parathyroid adenoma right 34 c d Fig. -J. Biersack and U. Heiden 4 Parathyroid Imaging 35 The subtraction technique with Sestamibi was first described by Coakley et al. in 1989 [6] and O’Doherty et al. in 1992 [7]. The protocol was based on the use of 123I as the thyroid agent: first, oral administration of 20 MBq 123I, 4 h later acquisition of a 5-min thyroid scan, and then iv injection of 200 MBq of 99mTc-Sestamibi followed by a dynamic acquisition.

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